Gökhan S Hotamisligil Selected Research

Therapeutics

1/2011	Inflammatory mechanisms in obesity.
8/2010	Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.
8/2009	Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.
11/2002	A central role for JNK in obesity and insulin resistance.
10/2002	Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Gökhan S Hotamisligil Research Topics

Disease

42	Obesity 12/2021 - 02/2002
37	Insulin Resistance 12/2021 - 06/2001
18	Inflammation (Inflammations) 12/2021 - 02/2002
18	Atherosclerosis 01/2016 - 06/2001
15	Type 2 Diabetes Mellitus (MODY) 12/2015 - 11/2002
10	Metabolic Diseases (Metabolic Disease) 12/2021 - 01/2007
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2007 - 10/2002
5	Fatty Liver 12/2015 - 10/2005
5	Neoplasms (Cancer) 02/2015 - 03/2008
3	Non-alcoholic Fatty Liver Disease 01/2021 - 09/2006
3	Hyperglycemia 01/2019 - 08/2006
3	Asthma (Bronchial Asthma) 02/2015 - 08/2006
3	Body Weight (Weight, Body) 08/2009 - 07/2006
2	Hyperinsulinism (Hyperinsulinemia) 01/2019 - 02/2006
2	Virus Diseases (Viral Diseases) 01/2017 - 04/2015
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2015 - 08/2012
2	Tuberous Sclerosis (Bourneville's Disease) 09/2014 - 03/2008
2	Glucose Intolerance 01/2011 - 08/2009
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2007 - 07/2003
1	Necrosis 10/2021
1	Abdominal Aortic Aneurysm 01/2020
1	Weight Gain 01/2019
1	Weight Loss (Weight Reduction) 01/2019
1	Burns 05/2017
1	Vascular Remodeling 04/2013
1	Hypoglycemia (Reactive Hypoglycemia) 01/2013
1	Anthrax 08/2012

Drug/Important Bio-Agent (IBA)

23	Fatty Acid-Binding ProteinsIBA 12/2021 - 06/2001
20	Insulin (Novolin)FDA Link 12/2021 - 10/2002
20	Glucose (Dextrose)FDA LinkGeneric 05/2017 - 04/2002
18	LipidsIBA 05/2017 - 06/2001
10	CytokinesIBA 12/2021 - 02/2002
9	Phosphotransferases (Kinase)IBA 12/2021 - 11/2002
9	Proteins (Proteins, Gene)FDA Link 01/2016 - 09/2004
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2006 - 02/2002
7	Fatty Acids (Saturated Fatty Acids)IBA 03/2014 - 07/2003
5	JNK Mitogen-Activated Protein KinasesIBA 04/2015 - 01/2007
4	AdipokinesIBA 10/2021 - 09/2006
4	Protein Isoforms (Isoforms)IBA 01/2016 - 04/2005
4	Apolipoproteins E (ApoE)IBA 04/2006 - 06/2001
3	Transcription Factors (Transcription Factor)IBA 01/2021 - 10/2004
3	Messenger RNA (mRNA)IBA 01/2021 - 08/2006
3	CholesterolIBA 01/2016 - 10/2005
3	Pharmaceutical PreparationsIBA 10/2015 - 06/2008
3	CalciumIBA 09/2015 - 05/2011
3	Double-Stranded RNA (RNA, Double Stranded)IBA 04/2015 - 08/2012
3	C-Reactive ProteinIBA 12/2010 - 07/2003
3	Interleukin-6 (Interleukin 6)IBA 08/2009 - 09/2003
3	LeptinIBA 10/2008 - 02/2002
3	Insulin ReceptorIBA 04/2006 - 11/2002
2	X-Box Binding Protein 1IBA 01/2021 - 02/2014
2	Prokaryotic Initiation Factor-2IBA 01/2021 - 04/2015
2	LDL Receptors (LDL Receptor)IBA 01/2016 - 06/2011
2	Hypoglycemic Agents (Hypoglycemics)IBA 06/2015 - 08/2006
2	Nonesterified Fatty Acids (NEFA)IBA 01/2013 - 11/2002
2	InflammasomesIBA 08/2012 - 02/2011
2	CarbohydratesIBA 08/2012 - 12/2010
2	Bile Acids and Salts (Bile Acids)IBA 08/2012 - 08/2010
2	palmitoleic acidIBA 12/2010 - 12/2010
2	Triglycerides (Triacylglycerol)IBA 12/2010 - 12/2010
2	ApolipoproteinsIBA 09/2004 - 06/2001
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 12/2021
1	Inositol (Myoinositol)IBA 12/2021
1	Hormones (Hormone)IBA 12/2021
1	SolutionsIBA 01/2021
1	leupeptinIBA 01/2021
1	Cre recombinaseIBA 01/2021
1	Beclin-1IBA 01/2021
1	Red Fluorescent ProteinIBA 01/2021
1	Ammonium Chloride (Sal Ammoniac)FDA Link 01/2021
1	ChromatinIBA 01/2021
1	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021
1	SaltsIBA 01/2021
1	TunicamycinIBA 01/2021
1	SerpinsIBA 01/2021
1	Connexin 43 (Connexin43)IBA 01/2021
1	ThapsigarginIBA 01/2021
1	Green Fluorescent ProteinsIBA 01/2021
1	Activating Transcription Factor 6IBA 01/2021
1	Interleukin-18 (Interleukin 18)IBA 01/2020
1	CatecholaminesIBA 01/2019
1	PropionatesIBA 01/2019
1	Glucagon (Glukagon)FDA Link 01/2019
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018
1	AcidsIBA 05/2017
1	Interferon Type IIBA 01/2017
1	Molecular Chaperones (Chaperone, Molecular)IBA 01/2016
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2016
1	Blood Glucose (Blood Sugar)IBA 12/2015
1	Monoclonal AntibodiesIBA 12/2015
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 07/2015
1	trans-activation responsive RNA-binding proteinIBA 04/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2014
1	Mechanistic Target of Rapamycin Complex 1IBA 09/2014
1	Eukaryotic Initiation Factor-2 (EIF 2)IBA 02/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2013

Therapy/Procedure

5	Therapeutics 01/2011 - 10/2002
4	Bone Marrow Transplantation (Transplantation, Bone Marrow) 07/2012 - 06/2001